KEY TAKEAWAYS
- Astragalus has been used for centuries to support immunity and vitality.
- Compounds in astragalus may lower inflammation linked to heart disease.
- Some studies show improvements in heart failure and myocarditis symptoms.
- Astragalus root side effects are usually mild but can include fever or interactions with medications.

When it comes to heart health, most people think of cholesterol, blood pressure, and exercise. But inflammation? That’s the hidden troublemaker nobody talks about enough. While doctors hand out pills to lower cholesterol or thin the blood, inflammation often sits quietly in the background, fueling heart disease. This is where astragalus root, a traditional Chinese herb turned trendy supplement, has started to get attention.
For centuries, astragalus has been used to boost energy and immunity. Now, researchers are looking into whether astragalus root extract can also protect the heart.
What Is Astragalus?
Astragalus, also known as huang qi or milk vetch, comes from the root of Astragalus membranaceus. It belongs to the legume family and has been used in Chinese medicine for thousands of years. Traditionally, it has been taken to boost energy, strengthen immunity, and help the body adapt to stress.
Most modern supplements are made from astragalus root extract, which concentrates compounds like astragaloside IV and astragalus polysaccharides. These are thought to have antioxidant and anti-inflammatory effects, making them the focus of new studies on heart health.
What Does The Science Says About Astragalus and Heart Health
In a clinical trial involving 90 patients over the age of 65 who had suffered a heart attack, one group received a patented astragalus root extract while the other group took a placebo. The results:
1. Reduction of Inflammation
Over 12 months, blood tests showed that the astragalus root extract group had up to a 62% reduction in inflammation compared to placebo. This is significant because inflammation is a major driver of coronary plaque rupture and complications after heart attack.
2. Improved Immunity
Unlike other anti-inflammatory drugs, which can weaken the immune system and raise infection risk, astragalus appeared to do the opposite. Patients taking astragalus root extract showed improvements in immune cell activity, suggesting that the extract may reduce harmful inflammation while still keeping the immune system strong.
3. Fewer Adverse Effects
The study also tracked side effects. Patients taking astragalus root extract had about 30% fewer adverse outcomes such as fever or new medical problems compared to the placebo group. This is especially notable for older adults recovering from a heart attack, since they are often at higher risk for complications.
Researchers now want to test astragalus root extract in larger trials to see if these benefits extend to reducing repeat heart attacks or even lowering death rates.
SUMMARY
Astragalus may help older people recover better after a heart attack. It can calm harmful swelling, make the body’s defenses stronger instead of weaker, and may even lower the chance of new health problems.
How Astragalus May Support the Heart
1. Heart Failure Support
Heart failure happens when the heart cannot pump blood effectively. Some studies suggest that astragalus root extract may help strengthen heart function when used alongside standard medications.
Patients with heart failure who added astragalus to their treatment plans often showed greater improvement than those on medication alone. This suggests that astragalus may enhance the effects of conventional therapies.
- Improved left ventricular ejection fraction (a measure of heart pumping strength)
- Better exercise tolerance in patients with chronic heart failure
- Reduction in hospital readmissions in some studies
Overall, astragalus may offer an added layer of support for people already following medical treatment for heart failure.
SUMMARY
Astragalus can give extra support to people with weak hearts. It may help the heart pump stronger, make it easier to move around without getting tired.
2. Myocarditis Relief
Myocarditis is inflammation of the heart muscle, and it can lead to dangerous complications if not managed properly. Early research suggests that astragalus may help reduce symptoms of myocarditis.
This effect is likely due to the herb’s ability to lower inflammation and oxidative stress in heart tissue. By calming these processes, astragalus could help preserve heart function and prevent further damage.
- Reduction in inflammatory markers in the heart muscle
- Possible symptom improvement in myocarditis patients
- Antioxidant protection that may slow progression of damage
SUMMARY
Astragalus may help calm swelling in the heart and protect it from damage. This can ease symptoms and support the heart so it stays healthier for longer.
3. Improved Circulation and Protection During Reduced Blood Flow
Another promising area of research focuses on ischemia, which is when blood flow to the heart is reduced. Astragaloside IV, one of the key compounds in astragalus, has been shown to protect heart tissue under these conditions.
A study shows astragalus improved blood flow, reduced tissue damage, and helped the heart muscle recover more effectively after injury.
- Protection against ischemia-reperfusion injury (damage when blood flow returns after being blocked)
- Better recovery of heart tissue and function
- Reduced levels of oxidative stress markers
SUMMARY
Astragalus may help protect the heart when blood flow is low. It can reduce damage, improve recovery, and keep the heart stronger after stress or injury.
Other Potential Benefits of Astragalus
While most interest is around heart health, astragalus has been studied for a wide range of conditions:
- Common cold and respiratory infections
- Chronic fatigue syndrome
- Hepatitis and other liver problems
- Asthma and allergies
- Some cancers (early-stage studies only)
Animal studies also suggest it may improve exercise stamina and reduce fatigue. Astragalus (often combined with other herbs) has been used to ease symptoms of chronic fatigue.
What Are The Astragalus Root Side Effects?
Astragalus is generally considered safe for most people when used in moderate amounts. In fact, patients taking astragalus had fewer side effects than those on placebo. Still, it’s not risk-free.
Possible Astragalus root side effects include:
- Fever or mild digestive upset
- Suppressed immune system at very high doses
- Drug interactions, especially with immune-suppressing medications
- Risks during pregnancy or breastfeeding (not enough safety data)
- Worsening autoimmune conditions such as lupus, rheumatoid arthritis, or multiple sclerosis
As with all supplements, it’s important to talk to a healthcare professional before starting astragalus root extract, especially if you take prescription medications or have chronic conditions.
But, Lifestyle and Nutrition Still Matter
Even with exciting research on herbs like astragalus, the basics of heart health remain the same. Eating an anti-inflammatory diet with fish, greens, and berries, staying active, managing stress, and sticking with prescribed medications are all proven strategies. Astragalus may someday become part of the toolkit, but it won’t replace the fundamentals.
The Bottom Line
Astragalus root is an ancient herb now under the microscope for modern heart health. Early evidence shows that astragalus root extract may reduce inflammation, improve immune function, and help patients recover after heart attack. Most people tolerate it well, though awareness of possible Astragalus root side effects is important.
The science is promising but still in its early stages. For now, astragalus remains a supplement with potential, something worth watching as researchers dig deeper into whether this ancient root truly deserves a place in future heart care.